Follistatin
Follistatin is an endogenous glycoprotein that functions as a high-affinity activin-binding protein, sequestering activin A and myostatin (GDF-8) to block their signaling through type II TGF-beta receptors. Research preparations typically use the recombinant truncated form (FS288 or FS315) for in vitro binding and neutralization studies in skeletal muscle and reproductive cell models. Follistatin is a foundational tool in TGF-beta superfamily signaling research, particularly for dissecting myostatin pathway pharmacology. Supplied lyophilized for in vitro research use only.
Select size
$210.00
- CAS
- 117628-82-7
- MW
- ~37,000 to 40,000 Da (recombinant); ~3780 Da (synthetic truncated form)
- Formula
- N/A (recombinant protein)
- Purity
- >=98.8 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is Follistatin?
Follistatin is a synthetic research compound studied in laboratory settings. It has molecular formula N/A (recombinant protein), a molecular weight of ~37,000 to 40,000 Da (recombinant); ~3780 Da (synthetic truncated form), CAS 117628-82-7. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoKinetics's Follistatin?
AminoKinetics supplies Follistatin at >=98.8% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is Follistatin supplied?
Follistatin is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.